Assessment of the efficiency of the Protective Cream HPS

Discover the assessment of the efficiency of the Protective Cream HPS for people suffering from metal hypersensitivities, such as Nickel, Chromium, and Cobalt.

Current context:

12 to 17 % of the European population shows a metals hypersensitivity, especially to Nickel, Chromium, and Cobalt. Prevalence is clearly higher among women, because of how these hypersensitizations appearIndeed, the risk of being allergic increases when the skin comes in contact with objects containing irritant metals. For example, when you get your ears pierced and when you wear costumes earrings, your body is more exposed to objects containing Nickel or other irritant metals.

Contact eczema is the most current demonstration of this hypersensitivity to NickelIt can lead to erythematic, pruritic or edematous lesions.

Figure 1 : working principle of the Protective Cream HPS

Studies have been done in order to:

  • determine the efficiency of this technology to prevent symptoms of contact dermatitis on healthy skin.

  • Estimate the impact of these products on a damaged skin  in association with dermatologists and allergists.


Under medical supervision, 52 volunteers have tested the efficiency of the Protective Cream HPS.

  • Efficiency on healthy skin:

To test the efficiency on healthy skin, 35 volunteers followed the following protocol:

  • Choice of an object known to lead to a cutaneous reaction (watch, earrings, costume jewelry, belt, jean button, shoes).
  • Application of the cream on the cutaneous zone in contact with this object and possible application of the cream directly on the object.
  • Wearing the object. We wrote down the time during which no symptom appeared.

A protection is considered effective if there is a total absence of symptoms after wearing the object known to lead to a skin reaction for at least 5 hours

  • Efficiency on damaged skin:

To test the efficiency on damaged skins, 17 patients were recruited by doctors. They used the Protective Cream HPS on their dermatitis with follow-up of the evolution of the lesions. Then the doctors reported the results to Skintifique.


  • Efficiency on healthy skin:

The results showed the efficiency of the protection for at least 5 hours for 79 % of the people which tested the Protective Cream HPS. This protection can last up to 18 hours for some of them.

For 13 % of the people, the protection did not meet the criteria to validate the efficiency of the product. One of the criteria is the absence of reaction during at least 5 hours. Finally, for the remaining 8 %, we were not able to determinate the efficiency of the product.It can be due to a misuse of the skin of the Protective Cream HPS.

  • Efficiency on damaged skin:

The tests on damaged skin have been done within the framework of consultations with dermatologists and allergists. Because of the confidentiality, fewer elements are available on the demography of these populations. 17 patients and users belonging to several professional categories tried the Protective Cream HPS: construction worker, hairdresser, cashier, nurse, beautician.

76,5 % of the people with damaged skin experimented a real improvement of their skin condition. The efficiency was insufficient or the test inconclusive for 23,5 % of them.

Some before/after pictures for damaged skin:

Man, paver, 55 years old, Nickel and Chromium allergy

Woman, employee, 35 years old, Nickel allergy


All the studies, both on healthy skin and on damaged skin, indicate that the Protective Cream HPS is efficient to help the people allergic to Nickel in at least 75 % of the cases.


Hydrating Gel Plus HS

An exceptionally pure head-to-toe moisturizing, soothing and repairing cream. Provides intense and long-lasting relief

Protective Cream HPS

The first cream in the world to protect the skin from irritant metals (Nickel, Chromium, Cobalt…) for up to 14h while letting it breathe

Moisturizing Lotion HP

A very pure moisturizing body lotion which hydrates and protects from pollution and metals (Nickel, Chromium…)

Cleanser P

An extremely pure, soft and efficient micellar water which cleanses, removes make-up, traces of pollution and metals (Nickel…)