About Ehlers-Danlos syndrome (or EDS)

Find on this page all information about Ehlers-Danlos syndrome (or EDS): what is it? What are its symptoms? What treatments exist? How can the Ehlers-Danlos syndrome be relieved?

What is Ehlers-Danlos syndrome?

Ehlers-Danlos syndrome, or EDS, is an illness which was first described at the beginning of the 20th century by the doctors Edvard Ehlers in Copenhagen and Alexandre Danlos in Paris. Initially described and characterised by a skin which was fragile, haemorrhagic and stretchable, and an excessive articular mobility, the EDS is a genetic disease which involves an anomaly of the connective tissue.

The syndromes of Ehlers-Danlos (EDS) form a heterogeneous group of hereditary illnesses of the connective tissue, characterised by an articular hyperlaxity, a cutaneous hyperelasticity and a tissular fragility. There are numerous forms of the EDS, distributed in 1997 in 6 classes, although in practice, three forms are mainly used: classic, hypermobile and vascular.

In these three forms, the disease manifests itself by similar symptoms, but with intensities of variable expression. The classic form is associated mainly with appearances on the skin, the hypermobile shape is characterised by more intense articular appearances and the vascular shape involves essentially arterial, intestinal and uterine appearances. It is in this last group that the most serious forms of the disease can be found, with a risk of ruptured arteries and internal organs. The EDS can declare itself at different stages of the life of an individual, most of the time during the childhood or during puberty.

Various epidemiological data place the prevalence of the disease between 1/5000 and 1/10 000 births, although these figures are discussed by certain doctors who plead for a much bigger incidence of the disease and question its classification as a rare disease.

Depending on the mutation type involved, transmission can be autosomal dominant or recessive dominant. In certain very rare cases, the transmission can be linked to the X.

Hormones could also be a predominant factor in the expression of the symptoms of the illness, which would explain the strong share of women amongst diagnosed patients, despite a transmission mode which is not linked to the idiochromosome.

What are the symptoms of Ehlers-Danlos syndrome?

Several symptoms are associated with EDS:

  • Fatigue
  • Chronic and diffused pains which are resistant to the usual analgesic treatments. These pains can be articular (the most frequent) and periarticular, muscular, abdominal, and migraines…
  • Proprioceptive and movement control disorders
  • Arthrochalasis
  • Alterations of the skin (thinness, fragility, stretch marks, difficult healing)
  • Numerous and spontaneous bruises and haemorrhage

Other appearances are often associated with EDS: digestive, respiratory, dental, ophthalmological, auditive or cognitive problems.

One of the essential markers of the illness is that it is family run, with appearances and levels which can be different in the same family.

EDS, unlike degenerative illnesses, is characterised by a state of fragility, and not a progressive deterioration of the patient’s state. Factors can improve or deteriorate the state of a patient: traumas aggravate the illness, feminine hormones play an important role (the illness can be worse during puberty and after giving birth, and sometimes improve during a pregnancy), and heat often improves symptoms.

How can Ehlers-Danlos syndrome be treated?

There are no treatments for this illness, but the symptoms can be taken care of. Ligament or digestive surgery must be considered with great precautions. Patient care can be done through re-education, orthosis, compression clothing, and the use of certain molecules has improved the comfort and state of some patients.

The skin must be treated with consideration and protected from physical aggressions, sun, heat and cold. It must be hydrated effectively.

How can Ehlers-Danlos syndrome be relieved?

Gel Hydratant Plus HS - Hydrating Gel Plus

The Hydrating Gel Plus HS developed by Skintifique has very strong hydrating and soothing properties. The skin of people suffering from Ehlers-Danlos syndrome needs this hydration, and this product is perfect for that.

Thanks to its innovative molecular structure and to its very pure composition (only 8 ingredients, all chosen with care), the Hydrating Gel Plus HS ensures a long-lasting hydration and soothing.

It is also absolutely not irritant because it contains very few ingredients, and 0% paraben, silicone, mineral oil, fragrance and EDTA.

 

 

 

 

Skintifique products

Hydrating Gel Plus HS

Hydrating Gel Plus HS

Hydrating Gel Plus HS

An exceptionally pure head-to-toe moisturising, soothing and repairing cream. Provides intense and long-lasting relief

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Protective Cream HPS

Protective Cream HPS

Protective Cream HPS

The first cream in the world to protect the skin from irritant metals (Nickel, Chromium, Cobalt…) for up to 14h while letting it breathe

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Moisturising Lotion HP

Moisturising Lotion HP  

Moisturising Lotion HP

A very pure moisturising body lotion which hydrates and protects from pollution and metals (Nickel, Chromium…)

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Cleanser P

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Cleanser P

An extremely pure, soft and efficient micellar water which cleanses, removes make-up, traces of pollution and metals (Nickel...)

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