Assessment of the effectiveness of the Protective Cream HPS

Current context

12 to 17 % of the European population shows a metals hypersensitivity, especially to Nickel, Chromium, and Cobalt. Prevalence is clearly higher among women, because of how these hypersensitizations appear. Indeed, the risk of being allergic increases when the skin comes in contact with objects containing irritant metals. For example, when you get your ears pierced and when you wear costumes earrings, your body is more exposed to objects containing Nickel or other irritant metals. Contact eczema is the most current demonstration of this hypersensitivity to Nickel. It can lead to erythematic, pruritic or edematous lesions.
Studies have been made in order to:
  • determine the effectiveness of this technology to prevent symptoms of contact dermatitis on healthy skin.

  • Estimate the impact of these products on a damaged skin  in association with dermatologists and allergists.


Under medical supervision, 52 volunteers have tested the effectiveness of the Protective Cream HPS.

Effectiveness on healthy skin

To test the efficiency on healthy skin, 35 volunteers followed the following protocol:

  • Choice of an object known to lead to a skin reaction (watch, earrings, costume jewelry, belt, jean button, shoes).
  • Applying of the cream on the cutaneous zone in contact with this object and possible application of the cream directly on the object.
  • Wearing the object. We wrote down the time during which no symptom appeared.

A protection is considered effective if there is a total absence of symptoms after wearing the object known to lead to a skin reaction for at least 5 hours.

Effectiveness on damaged skin

To test the effectiveness on damaged skins, 17 patients were recruited by doctors. They used the Protective Cream HPS on their dermatitis with follow-up of the evolution of the lesions. Then the doctors reported the results to Skintifique.


Efficiency on healthy skin

The results showed the effectiveness of the protection for at least 5 hours for 79 % of the people which tested the Protective Cream HPS. This protection can last up to 18 hours for some of them.

For 13 % of the people, the protection did not meet the criteria to validate the effectiveness of the product. One of the criteria is the absence of reaction during at least 5 hours.

Finally, for the remaining 8 %, we were not able to determinate the efficiency of the product. It can be due to a misuse of the skin of the Protective Cream HPS.

Efficiency on damaged skin

The tests on damaged skin have been done within the framework of consultations with dermatologists and allergists. Because of the confidentiality, fewer elements are available on the demography of these populations. 17 patients and users belonging to several professional categories tried the Protective Cream HPS: construction worker, hairdresser, cashier, nurse, beautician.

76,5 % of the people with damaged skin experimented a real improvement of their skin condition. The effectiveness was insufficient or the test inconclusive for 23,5 % of them.

Some before/after pictures for damaged skin:

Man, paver, 55 years old, Nickel and Chromium allergy​
Woman, employee, 35 years old, Nickel allergy​


All the studies, both on healthy skin and on damaged skin, indicate that the Protective Cream HPS is efficient to help the people allergic to Nickel in at least 75 % of the cases.
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